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Job : Senior Research Biologist, Chembiotek, Kolkata
Brought to you by : C-DRIVE   03 09 2010 06:09:52 +0000
Industry : Biotechnology
Role : Senior Research Biologist
Functional Area : Biopharma
Experience level:  3.0 to 4.0 years
Must Have Skills / Tags :

pharmacology

Additional Skills / Tags :

toxicology preclinical pk pd NCE FOB CNS BSL-2 Cell culture Xenopus GLP

 
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Roles and responsibility for Senior Research Biologist, Chembiotek, Kolkata :

1) Screening NCEs for safety pharmacology assessment with specific emphasis on cardiovascular, CNS and pulmonary studies. Design, planning and execution of in vitro, ex vivo (organ bath/Langendorff) and in vivo safety pharmacology experiments.
2) Hands-on expertise in cell culture; routine biochemical experiments; dosing, sampling and surgical procedures in rodents.
3) Expertise to develop Functional Observational Batteries (FOB) for safety assessment in rodents.
4) Well versed in Langendorff, Organ bath, ECG, BP/Heart rate, Respiration rate monitoring, Telemetry and MPVS/Power lab (ADI) instruments. Knowledge of Xenopus oocyte system and zebrafish models would be advantageous.
5) Well trained in BSL-2 (Bio safety level-2) norms and GLP (Good laboratory Practices) to prepare for various SOPs related to Safety pharmacology.

Requirements for Senior Research Biologist, Chembiotek, Kolkata :

MPharm / MVSc (Pharmacology & Toxicology) with 3 – 4 years in Drug discovery and Development (Preclinical Pharmacology).

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Chembiotek is a high end integrated contract research organization located in Kolkata, India. It complements the R D efforts of its global research partners in the area of synthetic organic chemistry, process chemistry, medicinal chemistry, combinatorial synthesis, Natural Product Chemistry,......